INTERNATIONAL CONGRESS OF
CancerGenetics
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1. Investigation of lncRNA HULC Expression in Reovirus-Infected Huh-7 Cells (Research Paper)
Reoviruses are oncolytic viruses that can destroy different cancer cells, such a...Read more
A Focused Review of Bioinformatics Pipelines for Circulating Tumor DNA (ctDNA) Analysis (Review)
The analysis of circulating tumor DNA (ctDNA) from blood, a key component of liq...Read more
A Network Pharmacology Investigation into the Multi-Target Mechanisms of Withalongolide A Against Pancreatic Cancer (Research Paper)
Pancreatic cancer remains one of the most lethal malignancies, characterized by ...Read more
A Review of Genetic and Epigenetic Alterations Underlying Hereditary and Sporadic Cancer Susceptibility (Review)
Cancer remains a leading cause of morbidity and mortality worldwide, with both i...Read more
A Review of the Regulatory Role of Long Non-Coding RNA GAS5 in Breast Cancer (Review)
Breast cancer (BC) is the most common malignancy among women worldwide. This dis...Read more
Advancements of Adenovirus-Based Gene Therapy in Colorectal Cancer (Review)
Despite the recent advances in controlling Colorectal cancer (CRC), CRC remains ...Read more
Aerobic Glycolysis Gene Overexpression and Prognostic Value in Pancreatic Ductal Adenocarcinoma: A Systematic Review (Review)
Pancreatic ductal adenocarcinoma (PDAC) exhibits a pronounced Warburg effect, wi...Read more
AKT1 as a central hub gene in miR-424/503 cluster-regulated oncogenic networks in cervical cancer (Research Paper)
The miR-424/503 cluster, located on the X chromosome, is implicated in various g...Read more
An Exploratory Transcriptomic Analysis of Granulosa Cells in Normal-Weight PCOS Women Suggests Altered DNA Repair and Signaling Pathways Linked to Cancer Risk (Research Paper)
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder often associate...Read more
Application of bioinformatics tools for the detection of germline BRCA1/BRCA2 variants in diagnostic NGS data: A Systematic Review (Review)
Inherited mutations in the tumor suppressor genes BRCA1 and BRCA2 markedly incre...Read more
Application of Gene Editing Technologies in the Treatment of Colorectal Cancer: A Novel Approach in Personalized Medicine (Review)
Colorectal cancer (CRC) is among the most prevalent and lethal cancers globally....Read more
Artificial Intelligence-Based Epigenetic Models for Predicting Hereditary Cancer Susceptibility (Review)
Hereditary cancers such as breast, ovarian, and colorectal cancers are often dri...Read more
Association Between Fluoroquinolone Antibiotic Exposure and Breast Cancer Risk or Progression: A Systematic Review (Review)
Breast cancer is one of the most common types of cancer among women, and identif...Read more
Bacterial Small RNAs Analogous to microRNAs: Roles in Stress Resistance and Extraterrestrial Survival (Review)
Bacterial small RNAs (sRNAs), functionally analogous to eukaryotic microRNAs (mi...Read more
Base Editing Approaches for Correcting TP53 and KRAS Mutations in Colorectal Cancer: A Systematic Review (Review)
Colorectal cancer is one of the most common and deadly cancers in the world. Col...Read more
Bioinformatics Analysis Identifies Shared lncRNAs Associated with CDH5 and PTPRB in the Adherens Junction Pathway of Lung Adenocarcinoma (Research Paper)
Despite the progress of medicine, lung cancer remains a public health issue and ...Read more
Bioinformatics in cance (Research Paper)
IntroductionBioinformatics is an interdisciplinary field that merges biology, co...Read more
Bioinformatics in Oncology: Tools, Challenges, and Clinical Applications (Review)
Cancer research has entered the era of big data, where bioinformatics plays a cr...Read more
BRCA 1/2 mutation and incidence of skin cancers: A Systematic Review and Meta-Analysis (Review)
Individuals with mutations in the BRCA1 and BRCA2 genes have a significantly inc...Read more
Can Multimodal Deep Learning Reveal Resistance Mechanisms and Improve Osimertinib Response Prediction in NSCLC? (Review)
Non-small cell lung cancer (NSCLC) with Epidermal Growth Factor Receptor (EGFR) ...Read more
Cancer Incidence and Mortality in Different Populations: The Role of Genetic Ancestry (Review)
Cancer is projected to remain the second leading cause of death globally in 2025...Read more
Chitosan-Functionalized Niosomes as a Dual-Action Delivery System for Spirulina maxima: Targeting Drug-Resistant Bacteria and Colorectal Cancer Cells (Research Paper)
The growing prevalence of multidrug-resistant (MDR) bacterial strains and the li...Read more
Clinical Relevance of CYP3A4 Polymorphisms rs2242480 and rs55951658 as Predictive Biomarkers in Breast Cancer Risk Assessment (Research Paper)
Breast cancer remains the leading cancer among women globally. Cytochrome P450 (...Read more
Comprehensive Bioinformatics Analysis Identifies INHBA and Its lncRNA Network as Key Drivers of Colorectal Cancer (Research Paper)
Colorectal cancer (CRC) originates from mutations in the epithelial tissues of t...Read more
Comprehensive Review and Meta-Analysis of Next-Generation Sequencing Applications in Lung Cancer: Focus on Mutation Identification (Review)
Lung cancer is one of the most common causes of cancer-related mortality in the ...Read more
CRISPR Models for Gene Knockout in Transcription-Coupled Repair and DNA-Protein Crosslink Outcomes in Lymphoid Leukemia (Review)
Lymphoid leukemias, which include both acute lymphoblastic leukemia (ALL) and ch...Read more
CRISPR-Based Restoration of TP53 Function in Glioblastoma: A Gene Editing Approach to Tumor Suppression (Review)
Glioblastoma (GBM) stands as the most aggressive primary brain tumor because pat...Read more
CRISPR-miRNA Synergy: Editing Tumor Suppressor miRNAs into Oncogenic "Dead Zones" (Review)
Tumor suppressor miRNAs are frequently silenced in cancer, contributing to thera...Read more
Decoding Retinoblastoma: Genetic and Epigenetic Foundations and Their Implications for Targeted Therapy (Review)
Retinoblastoma is a rare and aggressive intraocular malignancy that significantl...Read more
Design and Computational Analysis of CRISPR-Based Base Editors: Predicting Efficiency and Protein Stability for Precision Gene Editing (Review)
CRISPR-based base editors allow for precise single-nucleotide changes, without g...Read more
Dietary Fiber and Gut Microbiota in Colorectal Cancer: A Narrative Review (Review)
Colorectal cancer (CRC), as one of the most common causes of cancer-related deat...Read more
Discovery of Lung Cancer Biomarkers via Bioinformatics: Focus on the CAV1 Gene (Research Paper)
Lung cancer is currently the leading cause of cancer-related death worldwide (1)...Read more
Distribution of HLA Class I and II Alleles in Iranian patients with Myeloid leukemias: Insights into Genetic Predisposition (Research Paper)
Chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) are hematologica...Read more
Dual CRISPR Platforms for Oncovirus Therapy: Genome Eradication with Cas9/Prime Editing and RNA (Review)
Oncoviruses, including Hepatitis B Virus (HBV) and Epstein-Barr Virus (EBV), are...Read more
Dual Targeting of CD73/EGFR Axis via siRNA Nanocarriers: A Novel Immunotherapeutic Strategy Against Breast Cancer (Research Paper)
Targeting synergistic pathways in the tumor microenvironment (TME) is crucial fo...Read more
Effects of Anticancer Activity of Interferon Gamma on Colon Cancer Cell Lines: based on Network Pharmacology Analysis (Research Paper)
IFNs, especially IFN-γ, are secreted by immune cells such as monocytes and lymp...Read more
EGFR L861Q in Glioblastoma: From Computational Prediction of Structural destabilization to Clinical Correlation and Survival Impact (Research Paper)
Glioblastoma multiforme (GBM) represents the most aggressive primary brain tumor...Read more
Engineered exosomes in cancer gene therapy (Review)
Cancer is one of the most prevalent and lethal diseases globally. Currently used...Read more
Engineering and Production of a Recombinant HER3-Binding Affibody-EGFP Fusion Protein as a Potential Diagnostic Probe for Cancer Research (Research Paper)
HER3 (ErbB3) is a member of the receptor tyrosine kinase family that plays a key...Read more
Engineering the Gut Microbiome for Targeted Cancer Therapies (Review)
The human microbiome, a complex and dynamic ecosystem of microorganisms, is decr...Read more
Epigenetic Alterations in Hereditary Cancers: Diagnostic, Prognostic, and Therapeutic Insights (Review)
Epigenetics involves heritable changes in gene expression without altering the D...Read more
Epigenetic Alterations in Hereditary Cancers: Implications for Precision Oncology (Review)
Hereditary cancers, resulting from germline mutations in tumor suppressor genes ...Read more
Epigenetic Alterations in Hereditary Cancers: Mechanisms, Biomarkers, and Therapeutic Advances (Review)
Introduction: Hereditary cancers account for 5–10% of all malignancies and are...Read more
Epigenetic Alterations in Lymphoid Leukemia: The Role of DNA Methylation, Histone Modifications, and lncRNAs (Review)
Lymphoid leukemias, including acute lymphoblastic leukemia (ALL) and chronic lym...Read more
Epigenetic Alterations in Ovarian Cancer: Emerging Biomarkers for Diagnosis, Prognosis, and Innovative Therapeutic Strategies (Review)
Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. Early-s...Read more
Epigenetic Memory in Hereditary Cancers: Bridging Germline Mutations, Somatic Evolution, and Synthetic Therapeutic Vulnerabilities (Review)
Waddington's epigenetic memory is heredity of stable patterns of long-term gene ...Read more
Epigenetic Reactivation of Fetal Hemoglobin in Leukemia: A Mechanism of Clonal Advantage (Review)
Acquired fetal hemoglobin (HbF) expression is observed in acute erythroid leukem...Read more
Epigenetic Regulation and Therapeutic Implications in Hereditary Cancers (Review)
Epigenetic regulation refers to heritable and reversible changes in gene express...Read more
Epigenetic Regulation of EBV Reactivation in Immunocompromised Patients (Review)
Epstein-Barr virus (EBV), a member of the Gammaherpesvirinae subfamily, persiste...Read more
Epigenetic Regulation of MicroRNAs in Cancer: A Mechanistic Review with Clinical and Artificial Intelligence Perspectives (Review)
The emerging paradigm of epigenetic regulation has positioned microRNAs (miRNAs)...Read more
Epigenetic Therapies Against Virus-Driven Cancers: A New Frontier (Review)
Oncogenic viruses contribute to human cancer not only by integrating into host g...Read more
Epigenetically Regulated MicroRNAs in Oxaliplatin Resistance in Colorectal Cancer (Review)
Globally, colorectal cancer (CRC) continues to be the second most deadly kind of...Read more
Epigenetics and Cancer Signaling (Review)
IntroductionEpigenetics, the study of gene expression regulation without alterin...Read more
Epigenetics in Breast Cancer: From Molecular Mechanisms to Novel Therapeutic Approaches (Review)
Breast cancer, the most common malignancy in women, involves reversible epigenet...Read more
EV-Mediated Immune Modulation in Tumor Microenvironment (Review)
The tumor microenvironment (TME) is responsible for the area of the tumor which ...Read more
Evaluation of Common Polymorphisms in Brain Cancer and Assessment of Adverse Effects of Anticancer Drugs (Research Paper)
Cancer, characterized by uncontrolled cell growth and spread, ranks as the secon...Read more
Evaluation of miR-98-5P and GAB2 gene expression in endometriosis (Research Paper)
Background: GAB2 (Grb2-associated binding protein 2) is a member of the DOS/GAB ...Read more
Examination Binding and Specificity of New Luciferase-Affiprobe to Breast Cancer Cells (Review)
Engineered affiprobes that detect a particular target by target-dependent signal...Read more
Exosomal microRNAs as a therapeutic approach in breast cancer: A review (Review)
Breast cancer (BC) is the most common type of malignant disease in women and has...Read more
Exosomes biogenesis was increased in metformin-treated human ovary cancer cells; possibly to mediate resistance (Research Paper)
Exosome derived from tumor cells contribute to the pathogenesis of cancers. metf...Read more
Exploring the Role of TRIB3 in Temozolomide Resistance of Glioblastoma through a ceRNA Regulatory Network Analysis (Research Paper)
Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with limited th...Read more
Fecal extracellular vesicles as emerging mediators in microbiome–host communication and cancer metabolomics: a comprehensive review (Review)
Extracellular vesicles (EVs) are tiny particles encased in a lipid bilayer, rele...Read more
Feline Mammary Carcinoma – Challenges and Advances in Veterinary Oncology (Review)
Feline mammary carcinoma (FMC) is one of the most common neoplasms in older fema...Read more
Frequency and prognostic influence of ASXL1 mutations and its potential association with BCR-ABL1 transcript type and smoke in chronic myeloid leukemia patients (Research Paper)
Heterogeneous response to tyrosine kinase inhibitors (TKIs) and progress to adva...Read more
From Bench to Bedside: The Clinical Translation Gap in Cancer Nanomedicine (Review)
Nanoparticles hold great promise for tumor targeted drug delivery due to their a...Read more
From In Vitro Modeling to Clinical Applications: The Role of 3D Printing in Prostate Cancer Treatment (Review)
Prostate cancer (PCa) remains one of the most prevalent malignancies and a major...Read more
Gene Editing Strategies for Reactivation of BRCA1/2 in Breast Cancer (Review)
Breast cancer exists as one of the leading cancer types worldwide because BRCA1 ...Read more
Genetic Alterations in K-RAS, N-RAS, and BRAF Oncogenes in Metastatic Colorectal Cancer: A Frequency Analysis (Research Paper)
Colorectal cancer (CRC) is a major contributor to cancer-related deaths and is m...Read more
Genetic Polymorphisms of Cancer (Research Paper)
Genetic polymorphisms refer to the variations in DNA sequences that occur within...Read more
Genomic comparison of feline and human mammary tumors: new insights for cancer modeling. (Research Paper)
breast cancer , being the most prevalent from of cancer in women, has long b...Read more
Genomic interventions in oncology: Emerging Strategies to Address Cancer Therapy Limitations (Review)
Cancer continues to pose a formidable challenge to global health, with projectio...Read more
Genomic profiling of TMX2 reveals functional variants driving Gliobblastoma (Review)
Introduction: Glioblastoma Multiforme (GBM) is one of the most significant brain...Read more
Germline Polymorphisms in Chromatin Regulatory Genes Modulate Gut Microbiome and Colorectal Cancer Risk (Review)
Colorectal cancer (CRC) is the third most common cancer globally, underscoring t...Read more
Glioblastoma therapy enabled by magnetic nanocomplexes; Apoptosis signaling pathway analysis (Research Paper)
This study introduces an effective magnetohyperthermia (MH)-based therapy for de...Read more
Global and Regional DNA methylation of MMP2 and expression of DNA Methyltransferase in gastric adenocarcinoma (Research Paper)
The relationship between the expression level of matrix metalloproteinase -2 (MM...Read more
GLS1 Inhibition and Glutamine Addiction in MYC-Driven Burkitt Lymphoma: A Systematic Review (Review)
Burkitt lymphoma is characterized by MYC oncogene overexpression, which drives g...Read more
Gut Microbiome Influence on Gliomas and Their Impact on Tumor Immunity and Therapy (Review)
The human microbiome, which contains between 500 and 1000 bacterial species alon...Read more
Harnessing Oncolytic Viruses for Targeted Treatment of Triple-Negative Breast Cancer: Promises and Challenges (Review)
Considered an alternative treatment, some have argued that biological therapy ma...Read more
Helicobacter pylori and the Role of the Gastric Bacterial Microbiome in Gastric Cancer (Review)
More than a million new instances of gastric cancer were reported in 2018, makin...Read more
Histone Dysregulation and Hereditary Cancer Syndromes (Review)
1.1. The Epigenetic World of Cancer: Beyond the Genome The etiology of cancer, ...Read more
Identification of Molecular Targets for Gene Therapy in Canine Mammary Tumors Through Integrative Gene Network Analysis (Research Paper)
Canine mammary tumors (CMTs) are the most prevalent neoplasms in female dogs and...Read more
Identification of Stage-Specific Genes in Cervical Cancer Using Bioinformatics Tools (Research Paper)
Cervical cancer is the fourth most common cancer among women in the world. Previ...Read more
Immune-Related Genetic Polymorphisms as Predictors of Checkpoint Inhibitor Response in Solid Tumors (Review)
Immune checkpoint inhibitors (ICIs) targeting PD-1/PD-L1 and CTLA-4 pathways hav...Read more
Impact of Host Genome and Microbiome on Cancer Immunotherapy Response (Review)
A fundamental question in cancer immunotherapy is why patients with similar clin...Read more
Impact of Lipid Metabolism Reprogramming on Drug Resistance in Breast Cancer: A Systematic Review (Review)
Each year, more than 2.3 million women worldwide are diagnosed with breast cance...Read more
Integrated Bioinformatics Analysis Identifies CDCA7 and DLGAP5 as Key Genes with NEAT1-Mediated lncRNA Regulation in Chronic-Phase CML (Research Paper)
Chronic myeloid leukemia (CML) is a hematopoietic stem cell malignancy in which ...Read more
Integration of Systemic Metabolism and Immune Regulation: New Frontiers in Cancer Prevention and Therapy (Review)
Emerging evidence underscores the critical influence of systemic metabolic healt...Read more
Integrative Bioinformatics Analysis Identifies FYN and Its lncRNA–miRNA Network as Prognostic Biomarkers in Acute Myeloid Leukemia (Research Paper)
Acute myeloid leukemia (AML) is an aggressively advancing myeloid disorder ident...Read more
Integrative Bioinformatics to Identify Cell Cycle-Related Prognostic Biomarkers in Triple-Negative Breast Cancer (Research Paper)
Triple-negative Breast Cancer (TNBC) is the most aggressive subtype of breast ca...Read more
Integrative Multi-Omics Analysis for Personalized Cancer Therapy Combining genomics, proteomics, and metabolomics data from CPTAC or TARGET to design individualized treatments. - Bioinformatic A... (Review)
Introduction to Integrative Multi-Omics Analysis Integrative multi-omics anal...Read more
Investigating hsa-miR-193-3p and hsa-let-7e-3p and Their Target Genes IGFBP5 and AGPAT5 Associated with Fusobacterium nucleatum in Patients with Colorectal Polyps and CRC: In Silico Predictions and Experimental Validation (Research Paper)
Colorectal cancer (CRC) is among the most prevalent malignancies worldwide, ofte...Read more
Investigating the effect of aqueous extract of Centella asiatica plant on the expression of Bax and Bcl-2 genes in rat lung tissue during the process of cancer induction (Research Paper)
Lung cancer remains the leading cause of cancer-related mortality worldwide, wit...Read more
Investigating the interaction between the WNT2 gene as a potential biomarker and its associated miRNA in colorectal cancer through bioinformatics analysis (Research Paper)
Colorectal cancer is the third most common cancer and the second leading cause o...Read more
Investigating the Role of the Gut Microbiome in the Response to Melanoma Immunotherapy (Review)
Melanoma is a highly aggressive skin cancer that, in its advanced stages, is ass...Read more
Investigation of Common Genetic Variants Involved in Breast Cancer and the Interacting Roles of MicroRNAs and Obesity in Disease Pathogenesis (Research Paper)
Obesity, particularly in postmenopausal women, is a well-established independent...Read more
Investigation of Hexokinase Enzyme in Brain Cancer (Research Paper)
Brain cancer is one of the neoplastic tumors with complex clinical features that...Read more
Investigation of somatic mutations and polymorphisms of the KRAS and NRAS genes in colorectal cancer.' (Research Paper)
Colorectal cancer, also known as colon cancer, is a type of cancer that originat...Read more
Investigation of the Association Between HLA (HLA-A, B, DRB1) Alleles and Susceptibility to Acute Lymphoblastic Leukemia in Southern Iran (Research Paper)
Acute lymphoblastic leukemia (ALL) is a malignant disorder of the bone marrow ch...Read more
Lactate Dehydrogenase A Overexpression and Tumor Microenvironment Acidosis in Triple-Negative Breast Cancer: A Systematic Review (Review)
Triple-negative breast cancer (TNBC) relies heavily on glycolytic flux, driven b...Read more
LAT1 Amino Acid Transporter Overexpression and Tumor Growth in Glioblastoma: A Systematic Review (Review)
The large neutral amino acid transporter 1 (LAT1, SLC7A5) mediates uptake of ess...Read more
Leveraging tumor microenvironment metabolism for smart drug delivery systems (Review)
The tumor microenvironment (TME) is a metabolically reprogrammed environment whe...Read more
Liquid Biopsy in Cancer Detection: Advances, Applications, and Future Perspectives (Review)
Cancer remains one of the leading causes of mortality worldwide, with approximat...Read more
Mapping the Dark Genome: How Non Coding Drivers Fuel Cancer (Review)
The advent of large scale pan-cancer genomics initiatives has shown definitively...Read more
Merkel Cell Polyomavirus Large T-Antigen Mutations in Merkel Cell Carcinoma Pathogenesis: A Systematic Review (Review)
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin malignancy freq...Read more
Meta-Analysis on Gene Expression: the Therapeutic Efficacy of Inulin in Caco-2 Cancer Cells (Research Paper)
Colorectal cancer (CRC) is one of the most prevalent cancers globally. Strong ep...Read more
Metabolic Interactions in Cancer: A Contemporary Review of TME Crosstalk and Therapeutic Insights (Review)
Introduction: Cancer is increasingly recognized as a genetic and metabolic disea...Read more
METHYLATION PATTERN OF THE RUNX3 GENE AND ITS IMPACT ON RESPONSE TO IMATINIB THERAPY IN CHRONIC MYELOID LEUKEMIA (Research Paper)
Chronic Myelogenous Leukemia (CML) is a clonal stem cell disease with deregulate...Read more
Methylation-based testing in PBMCs as a promising biomarker for colorectal cancer diagnosis and prognosis (Review)
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mort...Read more
Molecular advances in the detection and management of the most common cancer among women over the past three years (Review)
Breast cancer is the most prevalent cancer among women globally and ranks as the...Read more
Multiscale Bioinformatic Modeling for CRISPR-Based Immune Cell Engineering: A Framework for Targeted Cancer Immunotherapy (Research Paper)
Cancer remains a major public health challenge, largely due to tumor cells’ ab...Read more
Network-Based Identification of Molecular Drivers and Therapeutic Targets in Canine Osteosarcoma (Research Paper)
Canine osteosarcoma is a clinically aggressive bone tumor that shares significan...Read more
Next-Generation Cancer Vaccines: mRNA Platforms and Personalized Neoantigen Approaches (Review)
General Definition of Cancer Vaccines Cancer vaccines are designed to stimula...Read more
Oncolytic Herpes Simplex Virus Therapy for Glioblastoma: A Systematic Review of Clinical Outcomes and Immunological Effects (Review)
Importance and Challenges of Treating Glioblastoma Glioblastoma (GBM) is recogn...Read more
Oncoviruses and Epigenetic Alterations: Double Drivers of Tumorigenesis (Review)
A subset of human cancers can be traced to persistent infections with specific o...Read more
Online platform of the prevision of genetics cancer (Review)
Artificial Intelligence (AI) and Genetic Cancer Prevention: A Comprehensive Over...Read more
Oral Microbiome–Driven Inflammatory Pathways in Head and Neck Squamous Cell Carcinoma: A Systematic Review (Review)
Head and neck squamous cell carcinoma (HNSCC) exhibits a distinct oral microbial...Read more
Peptide-Based Nanocarriers for Overcoming the Blood-Brain Barrier in Glioblastoma Therapy (Review)
Glioblastoma (GBM) is recognized as the most aggressive primary brain tumor, cha...Read more
Peripheral blood IGF2 hypomethylation as a promising non-invasive indicator of colorectal cancer prognosis (Research Paper)
Conventional colorectal cancer (CRC) screening methods are hindered by invasiven...Read more
Physiological Alterations and Gene Regulation in the Tumor Microenvironment (Review)
Tumors are among the most significant threats to human health due to their aggre...Read more
Polymorphisms in Tumor Suppressor Genes (TP53, BRCA1/2) and Cancer Risk Modulation (Review)
Germline alterations in tumor suppressor genes, particularly BRCA1, BRCA2, and T...Read more
Precision CRISPR-Cas9 Targeting of PD-1 in T Cells for Enhanced Immunotherapeutic Response in Solid Tumors : A Systematic Review (Review)
The Programmed cell death protein 1(PD-1) receptor is a crucial inhibitory recep...Read more
Prognostic Circulatory Non-coding RNAs and Their Potential Targets in Human Breast Cancer (Research Paper)
Breast cancer (BC), a disease with both genetic and environmental roots, remains...Read more
Progress in Hepatocellular Carcinoma: Transitioning from Molecular Diagnostics to Targeted Treatments and Genomic Insights (Review)
Introduction: Hepatocellular carcinoma (HCC) is recognized as the most prevalen...Read more
Pseudogenes in colorectal cancer: A systematic review (Review)
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worl...Read more
Reduced KCNA1 Expression Predicts Prognosis and Metastatic Potential in Papillary Thyroid Carcinoma (Research Paper)
Papillary thyroid carcinoma (PTC) represents a prevalent and well-differentiated...Read more
Role of Epigenetically Regulated microRNAs in Gemcitabine Resistance in Pancreatic Cancer (Review)
Pancreatic cancer (PC) has a five-year survival rate of less than 10%, making it...Read more
Role of non-coding RNAs in the regulation of Urothelial bladder cancer stem-ness (Review)
Urothelial bladder cancer (UBC), the most common malignancy of the urinary tract...Read more
Selective Detection of HER3-Positive Breast Cancer Cells Using a Novel Affibody-EGFP Biosensor (Research Paper)
Breast cancer continues to be a leading cause of cancer-related death among wome...Read more
Single Nucleotide Polymorphisms (SNPs) in Lung Cancer: Genetic Risk Factors, Functional Mechanisms, and Clinical Implications (Review)
abstract Lung cancer continues to be a major cause of cancer-related death glo...Read more
siRNA-Mediated Knockdown of BUB1 Impairs Growth and Metastatic Potential in Pheochromocytoma Cells (Research Paper)
Pheochromocytoma and paraganglioma (PPGLs) are rare neuroendocrine tumors with l...Read more
Synthetic Lethality Approaches Using Gene Editing for Targeting Cancer Vulnerabilities (Review)
Synthetic lethality occurs when simultaneous inactivation of two genes results i...Read more
Systems Biology Approach Reveals ESR1 and CDK1 Regulatory Axis with miRNA–lncRNA Network as Novel Biomarkers in Uterine Corpus Endometrial Carcinoma (Research Paper)
Unregulated growth of uterine cells causes uterine cancer (or womb cancer). Endo...Read more
Targeted Detection of HER3-Expressing Cancer Cells via a Novel Bioluminescent Affibody (Research Paper)
Breast cancer ranks as the second most frequently diagnosed cancer across both s...Read more
Targeting Breast Cancer Stem Cells with CAR-T Cells: A Novel Approach (Review)
Breast cancer is one of the most common and lethal malignancies affecting women ...Read more
The effect of extracellular polysaccharides (EPS) from Lactobacillus casei on advanced liver cancer (Research Paper)
Liver cancer is the third leading cause of cancer death in the world. Current tr...Read more
The effect of genistein supplementation on the gut microbiome and its role in inhibiting breast tumors (Review)
Breast cancer (BC) is the most common cancer among women globally, leading to hi...Read more
The gut microbiom and colorectal cancer: a new frontier in aging, inflammation and therapeutic responses (Review)
The gut microbiome, a highly dynamic and diverse microbial ecosystem withnin the...Read more
The Gut Microbiome as a Determinant of Immunotherapy Response in Metastatic Melanoma (Review)
The gut microbiome has emerged as a pivotal regulator of immune checkpoint inhib...Read more
The Gut Microbiome's Role in Colorectal Cancer Prognosis and Immunotherapy Response (Review)
Colorectal cancer (CRC) is a major global health concern, ranking as the third m...Read more
The Gut Microbiome's Role in Modulating PD-1/PD-L1 Immunotherapy Efficacy in Melanoma (Review)
The relationship between gut microbial communities and immune checkpoint inhibit...Read more
The Human Microbiome in Cancer: Mechanisms, Biomarkers, and Therapeutic Potentials (Review)
Emerging evidence highlights the pivotal role of the human microbiome—particul...Read more
The impact of the gut microbiome on the effectiveness of cancer immunotherapy (Review)
Introduction The gut microbiome is known to be a critical factor in regulating i...Read more
The interaction of lncRNA and mRNA in Esophageal Squamous Cell Carcinoma (Research Paper)
Esophageal squamous cell carcinoma (ESCC), a highly aggressive malignancy, accou...Read more
The Interplay of HPV Oncoproteins, Tumor Microenvironment, and Extracellular Vesicles in Cervical Cancer Progression (Review)
Cervical cancer (CC) is a major global health concern, ranking as the fourth mos...Read more
The microbiome and its role in the development of breast cancer (Review)
Despite extensive strategies in the diagnosis and treatment of cancer, breast ca...Read more
The role of AI in the diagnostic and treatment of the most common cancers with epigenetic roots: surveying its effectiveness in Iranian patients (Review)
Epigenetic studies have shown that reversible changes in gene expression occur w...Read more
The Role of Epigenetics in the Prevention and Treatment of Hereditary Colorectal Cancer through Nutrition and Targeted Therapies. (Review)
Epigenetic studies have elucidated the dynamic relationship between nutrition an...Read more
The Role of Gut Microbiome in Colorectal Cancer (Review)
Colorectal cancer (CRC) is one of the most common malignancies worldwide, posing...Read more
The Role of Promoter Hypermethylation in BRCA1/2 Mutation Carriers and the Risk of Triple-Negative Breast Cancer (Review)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype with...Read more
The Role of S100B Protein in Promoting Metastasis in Small Cell Lung Cancer: Molecular Mechanisms and Therapeutic Implications – A Narrative Review (Review)
Small cell lung cancer (SCLC) is a well-established, highly malignant neuroendoc...Read more
The Role of SCFAs Derived from Gut Microbiota in Colorectal Cancer Progression; A Systematic Overview (Review)
Colorectal cancer is one of the leading causes of cancer-related deaths worldwid...Read more
The Role of the Human Microbiome in Cancer Development and Therapy Response (Review)
The human microbiome, encompassing trillions of microorganisms residing in and o...Read more
The Role of the Microbiome in Cancer Prevention and Therapy (Review)
The gut microbiome, consisting of bacteria, fungi, and viruses, is crucial for h...Read more
The Role of the Urinary Microbiome in Prostate Cancer Progression: From Early Detection to Targeted Therapy (Review)
Prostate cancer (PCa) is one of the most prevalent malignancies in men, with ear...Read more
The suppressive role of the bone marrow microenvironment on natural killer cells’ anti-leukemic activity in acute myeloid leukemia (Review)
Acute myeloid leukemia (AML) is the most prevalent type of acute leukemia in adu...Read more
The Tumor Microenvironment and Immunotherapy Response: Challenges and Opportunities in Precision Oncology (Review)
Cancer immunotherapy has emerged as a transformative approach in oncology, lever...Read more
The Vaginal Microbiome and HPV-Driven Carcinogenesis: A Structured Review (Review)
Persistent infection with high-risk human papillomavirus (hrHPV) is necessary bu...Read more
The Warburg Effect and Cancer Progression: Glycolytic Reprogramming, Epigenetic Modifications, and Therapeutic Perspectives (Review)
Cancer cells require vast amounts of nutrients for continuous growth, leading to...Read more
Therapeutic Genome Editing of TP53 and KRAS in Solid Tumors: A Comprehensive Review of CRISPR-Cas9 Applications (Review)
The advent of CRISPR-Cas9 genome editing has opened unprecedented opportunities ...Read more
Therapeutic potential of miRNA modulation to overcome Temozolomide resistance in Glioblastoma (Review)
Glioblastoma (GBM) is the most aggressive and lethal primary brain tumor in adul...Read more
Thermostabilization and Structural Optimization of Cas9 Variants Using Protein Stability Predictions and AlphaFold Modeling (Review)
CRISPR-Cas9 genome editing is an extremely effective tool; however, its use in t...Read more
Tissue Engineering Scaffolds Loaded With a Variety of Plant Extracts: Novel Model in Breast Cancer Therapy (Review)
Despite notable advances in breast cancer (BC) diagnosis and treatment, it remai...Read more
Title: High-grade leiomyosarcoma with constitutional homozygous PTEN p.Pro95Arg and tumor APC/NBN VUS on paired WES (Research Paper)
PTEN hamartoma tumor syndrome (PHTS) is associated with diverse malignancies; it...Read more
Unlocking Nature's Arsenal: The Expanding Therapeutic Role of Berberine in Combating Lung Cancer (Review)
Lung cancer remains the most formidable adversary in the field of oncology, dist...Read more
Unraveling the Role of FGFR3 in Melanoma Progression: An Integrated Bioinformatics Approach to mRNA Expression and ceRNA Network Analysis. (Research Paper)
Melanoma, the most aggressive and deadliest form of skin cancer, originates from...Read more
Unveiling Molecular Mechanisms and Biomarkers for Colitis-Associated Colorectal Cancer in Ulcerative Colitis (Research Paper)
Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohnâ€...Read more
Using Three Machine Learning Techniques for Predicting Breast Cancer Recurrence (Review)
Despite advances in breast cancer diagnosis and treatment, recurrence remains a ...Read more
Utilizing WGCNA to uncover E2F8 and SPC24 as promising therapeutic targets in breast cancer (Research Paper)
Breast cancer is one of the leading causes of cancer-related mortality among wom...Read more
Wnt/β-catenin Signaling Pathway Mediated by the Gut Microbiome: The Influence of Fusobacterium nucleatum on Colorectal Cancer Progression (Review)
Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the seco...Read more
