INTERNATIONAL CONGRESS OF
CancerGenetics
Genetic Polymorphisms of Cancer
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Kimiya yarahmadi,1,* Sogol taher,2
- Introduction: Genetic polymorphisms refer to the variations in DNA sequences that occur within a population, where two or more distinct alleles exist for a particular gene. These variations can influence various traits, including susceptibility to diseases like cancer. In cancer research, understanding genetic polymorphisms is crucial as they can affect how individuals respond to environmental factors, treatments, and their overall cancer risk. Some genetic variants may increase the likelihood of developing certain types of cancer, while others may provide a protective effect.
- Methods: Genetic polymorphisms can significantly influence cancer development and progression through various mechanisms. At the core of these mechanisms are mutations, which are changes in the DNA sequence that can occur in different genes. These mutations can either promote cancer by disrupting normal cellular functions or, in some cases, reduce risk by enhancing DNA repair processes. When mutations occur in key genes related to cell growth and division, they can lead to uncontrolled cell proliferation, a hallmark of cancer.
- Results: Future directions in cancer genetics promise to transform how we understand and treat this complex disease. Emerging technologies, such as advanced genomic sequencing and CRISPR gene editing, are paving the way for more precise analysis of genetic variations. These tools allow researchers to map out the intricate details of cancer genomes, identifying mutations that drive tumor growth and resistance to therapies.
- Conclusion: As research continues, the focus will increasingly shift toward understanding how these genetic variations affect responses to treatment. This knowledge can guide the development of more effective strategies, leading to better survival rates and quality of life for cancer patients. Overall, the future of cancer genetics is bright, with the promise of innovative therapies that are more aligned with the complexities of cancer itself.
- Keywords: Future Directions in Cancer Genetics
