INTERNATIONAL CONGRESS OF
CancerGenetics
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6-Gingerol (PubChem CID 442793): Integrated Curated and In Silico Analysis of Cancer-Relevant Molecular Associations and Predicted Candidate Targets (Review)
Introduction 6-Gingerol is a major bioactive phenolic compound of Zingiber offi...Read more
A Practical Framework for Modeling and Engineering the Bone Marrow Tumor Microenvironment, Focusing on Key Parameters and Therapeutic Applications (Review)
Hematologic malignancies are a group of cancers that disrupt hematopoiesis in th...Read more
A review context on the current concepts of gene therapy (Review)
Introduction: Gene therapy is 21 century medical technique that treats disease...Read more
A Review of Gene therapy in cancer (Review)
According to the definition of the World Health Organization (WHO), cancer is th...Read more
A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer (Research Paper)
Colorectal cancer (CRC) is a globally prevalent malignancy, primarily affecting ...Read more
Adenoviral Vector-Mediated Monoclonal Antibody Gene Delivery in Cancer Immunotherapy: Opportunities and Challenges (Review)
Monoclonal antibodies (mAbs) represent the gold standard in targeted cancer ther...Read more
An Analytical Review of Multi-Omics Integration and Bioinformatics Tools in Precision Oncology (Review)
Traditional pathological markers fail to address the spatiotemporal heterogeneit...Read more
An update on application of niosomes for delivering miRNA, siRNA, and anticancer drugs: A review (Review)
Effective delivery of therapeutic agents to cancer cells remains a major challen...Read more
Analytical Review of Novel Gene Therapy and Gene Editing (CRISPR) Approaches in Molecular Targeting of Cancer: Challenges and Future Horizons in Medical Biotechnology” (Review)
Cancer, as one of the leading causes of global mortality, demands more precise a...Read more
Antibacterial and Antibiofilm Activity of Lactobacillus-Derived Cell-Free Supernatants Against Multidrug-Resistant Pseudomonas aeruginosa: Synergistic Effects With Antibiotics and Suppression of Biofilm-Associated Genes (Research Paper)
Multidrug-resistant (MDR) Pseudomonas aeruginosa is a major cause of difficult-t...Read more
Antitumor Effects of Phenols and Peptides from Streptomyces violaceochromogenes M12 on Breast Cancer in Mice (Research Paper)
Breast cancer is the most common cancer worldwide and a major cause of cancer-re...Read more
Antitumor activities of a novel fluorinated small molecule (A1) in CT26 colorectal cancer cells: molecular docking and in vitro studies (Research Paper)
Chemotherapeutic treatment of colorectal cancer (CRC) has not been satisfactory ...Read more
Application of Artificial Intelligence in Cancer Radiology and Prediction of Tumor Surgical Outcomes: A Systematic Review of Radiomic Models and Multimodal Approaches (Review)
Early and accurate cancer diagnosis along with reliable prediction of surgical o...Read more
Application of Artificial Intelligence in the Diagnosis of Lung Cancer from Pathology Slides: A Systematic Review (Review)
Lung cancer is the second most common cancer and the leading cause of cancer-rel...Read more
Artificial Intelligence and Bioinformatics in Cancer: From Multi-Omics Integration to Precision Immunotherapy (Review)
Background: The convergence of artificial intelligence (AI) and bioinformatics h...Read more
Artificial Intelligence and Machine Learning–Driven Interpretation of Non-Coding and Structural Variants in Cancer Genomics (Review)
Over 98% of the human genome is noncoding, yet most cancer genetics has focused ...Read more
Artificial Intelligence for Precision Diagnosis, Prognostic Prediction, and Personalized Treatment of HPV-Associated Cervical Cancer: From Bench to Bedside (Review)
Early detection of unusual cervical cells improves the likelihood of prompt cerv...Read more
Artificial Intelligence in Lung Cancer Genomics: A Brief Review (Review)
Lung cancer exhibits substantial molecular heterogeneity, leading to pronounced ...Read more
Artificial Intelligence in Precision Breast Cancer Care: From Early Detection to Personalized Therapeutic Decision-Making (Review)
Breast cancer is a major cause of death among women around the world. Clinical r...Read more
Artificial Intelligence Strategies in Clinical Pathology and Radiology for Cancer Diagnosis: A Systematic Review (Review)
Early and accurate cancer diagnosis plays a pivotal role in the prognosis and qu...Read more
Association Between Metabolic Syndrome and Colorectal Cancer Risk and Mortality: Insights from Epidemiological, Genetic, and Molecular Evidence (Review)
Colorectal cancer (CRC) remains one of the most common malignancies worldwide, a...Read more
Association between rs6850524 Polymorphism in the CLOCK gene and susceptibility to breast cancer in Women from East Azerbaijan Province, Iran (Research Paper)
Breast cancer is a common malignancy in women , and circadian-clock genes have b...Read more
Association of interleukin-17A and chemokine/vascular endothelial growth factor-induced angiogenesis in newly diagnosed patients with bladder cancer (Research Paper)
Bladder cancer (BC) is known as one of the most com- mon types of urinary tract...Read more
Beyond BRCA1/2: Germline Pathogenic Variants in Fanconi Anemia Pathway Genes Identified Through Whole-Exome Reanalysis in Early-Onset Breast Cancer (Research Paper)
Whole-exome sequencing (WES) has expanded hereditary cancer evaluation beyond es...Read more
Bidirectional Dysregulation of Unprocessed Pseudogene Expression in Testicular Germ Cell Tumors (Research Paper)
Testicular germ cell tumors (TGCTs) arise within a tissue governed by highly spe...Read more
Bioinformatics analysis investigating the association between the potential biomarker MMP10 gene and its related miRNA in leukemia. (Research Paper)
Leukemia is the most prevalent form of cancer among children aged 0–14 years. ...Read more
Bioinformatics analysis of potential core genes for Esophageal squamous cell carcinoma (Research Paper)
Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with...Read more
Breast Cancer and the Microbiota: Insights into Disease Development and Progression (Review)
Breast cancer is shaped by genetic and cellular alterations as well as interacti...Read more
Cationic Liposome-Encapsulated Adenoviruses: Overcoming CAR-Dependent Resistance & Systemic Antitumor Immunity (Review)
Oncolytic virotherapy using recombinant adenoviruses represents a promising ther...Read more
cfDNA Methylation in Liquid Biopsy: Current Perspectives and Future Directions for Early Cancer Detection (Review)
Cancer remains the leading cause of death worldwide,and early detection is criti...Read more
Challenges and Emerging Strategies of CAR-T Cell Therapy in Solid Tumors: A Narrative Review (Review)
CAR-T cell therapy has revolutionized the treatment of several hematological mal...Read more
Circular RNAs in Hepatocellular Carcinoma: Molecular Mechanisms, Tumor Microenvironment, Therapeutic Resistance, and Clinical Potential (Review)
Circular RNAs (circRNAs) are stable, covalently closed RNA molecules generated m...Read more
Circulating piRNAs in Colorectal Cancer: From Biomarker Discovery to Clinical Monitoring (Review)
Colorectal cancer (CRC) is among the commonest cancer types found across the glo...Read more
Combined application of nanotechnology and artificial intelligence in cancer radiology: A systematic review (Review)
Early and accurate cancer diagnosis has always been one of the fundamental chall...Read more
Comparative Transcriptomic and Network-Based Analysis of the Tumor Core and Peritumoral Margin in Glioma (Research Paper)
Gliomas exhibit marked spatial heterogeneity, with molecular and cellular differ...Read more
Comparison of mTOR gene expression in the kidney tissue of rats treated with DMBA and an aqueous extract of Centella asiatica (Research Paper)
7,12-Dimethylbenz[a]anthracene (DMBA) is a carcinogenic compound whose exposure ...Read more
CORRECTED! Microbial Genotoxicity, Epigenetic Reprogramming, Host Genotype, and Oncogenic Signaling in Cancer: A Mechanistic Review of Host-Microbiome Crosstalk (Review)
The intestinal microbiome is increasingly recognized as an active mechanistic co...Read more
CRISPR-Engineered Akkermansia muciniphila Synergizes with Intratumoral Microbiome Remodeling to Overcome Immunotherapy Resistance in KRAS-Mutant Colorectal Cancer (Research Paper)
Colorectal cancer (CRC) remains the third most common malignancy worldwide, with...Read more
CRISPR-Engineered Microbiome as Living Therapeutics for Colorectal Cancer: Targeted Elimination of Oncogenic Fusobacterium nucleatum and Neutralization of Colibactin Genotoxicity (Research Paper)
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worl...Read more
Cross-Cancer Transcriptomic Profiling Reveals Context-Dependent Conservation of Mesenchymal Programs Associated with Immune Checkpoint Inhibitor Resistance (Research Paper)
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; however, on...Read more
Cross-Cohort Transcriptomic Meta-Analysis Identifies GAB1 as a Reproducible Signal of Platinum Resistance in High-Grade Serous Ovarian Cancer (Research Paper)
High-grade serous ovarian cancer (HGSOC) is commonly treated with platinum-based...Read more
Cutaneous Angiosarcoma in an Afghan Hound: Clinical Pitfalls of Chemical Cauterization, Surgical Management, and Genomic Perspectives in Comparative Oncology (Research Paper)
Angiosarcoma (hemangiosarcoma) is an aggressive malignant vascular neoplasm orig...Read more
CXCL1, CXCL10 and CXCL12 Chemokines are Variously Expressed in Acute Myeloid Leukemia Patients Prior and Post Bone Marrow Transplantation (Research Paper)
The malignancy state of AML (acute myeloid leukemia) is characterized as th...Read more
Deciphering Tumor Molecular Heterogeneity in the Era of Precision Medicine. (Review)
Molecular and cellular heterogeneity are fundamental characteristics of tumors a...Read more
Decoupling Cellular Rejuvenation from Oncogenic Plasticity: A Single-Cell and Multi-Omic Framework for Identity-Preserving Partial Reprogramming (Review)
Partial reprogramming can reverse selected molecular features of aging and impro...Read more
Development and Immunological Application of Bispecific Antibodies in the Treatment of Gastric Cancer (Review)
Gastric cancer (GC) is one of the leading causes of death related to cancer worl...Read more
Development of a Microbiome–Immune–Metabolic Biomarker Panel for Predicting Implantation and Live-Birth Outcomes in Assisted Reproductive Technology (Research Paper)
Infertility affects a substantial proportion of reproductive-aged couples, and a...Read more
Diagnostic Value of Circulating Long Non-coding RNAs in Liver Fibrosis, Cirrhosis, and Hepatocellular Carcinoma (Review)
The liver plays a central role in metabolic homeostasis and in regulating the im...Read more
Differential expression of LncRNA ITPK1-AS1 gene expression in gastric cancer (Research Paper)
Gastric cancer (GC) is the most common cancer type in worldwide. Detection of va...Read more
Dynamic Systems Modeling of Transient Photobiomodulation and Persistent Meningeal Lymphatic Endothelial Activation (Research Paper)
Background: Meningeal lymphatic vessels (MLVs) support cerebrospinal fluid drain...Read more
Effects of Curcumin Supplementation on Inflammatory, Oxidative Stress, and Anticancer Markers in Patients with Chronic Myeloid Leukemia: A Systematic Review (Review)
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm driven by the BC...Read more
Effects of Sialic Acid and Temozolomide on GFAP Gene Expression in the 1321N1 Glioma Cell Line (Research Paper)
Glioma is one of the most aggressive primary tumors of the central nervous syste...Read more
Efficacy and Safety of Immune Checkpoint Inhibitors in MSI-High Colorectal Cancer (Research Paper)
Background: Colorectal cancer (CRC) is the third most common malignancy worldwid...Read more
Efficacy and Safety of Immune Checkpoint Inhibitors in MSI‑High Colorectal Cancer (Research Paper)
Background: Colorectal cancer (CRC) is the third most common malignancy worldwid...Read more
Electro-Ionic Tumor Microenvironment as a Design Cue for Engineering Smart Drug Delivery Systems (Review)
The tumor microenvironment (TME) is characterized not only by biochemical abnorm...Read more
EMERGING MOLECULAR TARGETS AND MECHANISMS OF DRUG RESISTANCE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: TOWARD PERSONALIZED OPHTHALMIC THERAPY (Review)
Neovascular diseases of the retina and choroid, such as neovascular age-related ...Read more
Engineering Bacterial cellulose for Cancer Drug Delivery: From Controlled Release to Therapeutic Applications (Review)
Cancer chemotherapy is often limited by systemic toxicity, poor drug distributio...Read more
Epidemiological Analysis of the Frequency of Epstein-Barr Virus (EBV) and Human Papillomavirus (HPV) in Head and Neck Masses: A Comparative Study in Selected Carcinoma Subgroups (Sinus, Pharynx, Larynx) in Mashhad (Review)
Background and Aim: Head and neck cancers (HNCs) account for more than 660,000 n...Read more
Epigenetic and Metabolic Networks Shaping CAR-T Cell Exhaustion and Memory (Review)
Chimeric antigen receptor (CAR)-T cell therapy has transformed the treatment of ...Read more
Epigenetic Footprints of Cancer in Cell-Free DNA and Their Applications in Early Cancer Detection (Review)
Cell-free DNA, or cfDNA, consists of DNA fragments that are released from cells ...Read more
Epigenetically Regulated MicroRNAs in Oxaliplatin Resistance in Colorectal Cancer (Review)
Globally, colorectal cancer (CRC) continues to be the second most deadly kind of...Read more
Epstein–Barr Virus-Encoded MicroRNAs in Gastric Cancer: Linking Viral Epigenetic Regulation to Tumor Progression and Clinical Outcome (Review)
Epstein–Barr virus (EBV) is an oncogenic herpesvirus implicated in a distinct ...Read more
Eugenol as a Novel Antibiotic Adjuvant Against Carbapenem-Resistant Acinetobacter baumannii: Synergistic Activity With Carbapenems and Downregulation of OXA-51 (Research Paper)
Carbapenem-resistant Acinetobacter baumannii is an important multidrug-resistant...Read more
Evaluation of a Recombinant HPV Based Therapeutic Vaccine in a Murine Model of Cervical Cancer (Research Paper)
Background: Human papillomavirus (HPV) infection is the primary cause of over 95...Read more
Evaluation of circulating concentrations of CXCL1 (Gro-α), CXCL10 (IP-10) and CXCL12 (SDF-1) in ALL patients prior and post bone marrow transplantation (Research Paper)
The immune system plays an important role in the development of leukemia. CXC ch...Read more
Evaluation of miR-622 and OCT4 Expression in Breast Cancer Cells Treated with Extracellular Vesicles Derived from Stromal Cells (Research Paper)
Breast cancer is one of the most common cancers in women and remains a major cau...Read more
Evaluation of Newcastle Disease Virus-Induced Natural Killer Cell Activation and Its Potential Antitumor Effects (Review)
Natural killer (NK) cells are a prominent population of innate lymphoid cells (I...Read more
Evaluation of the CCL17/CCL22-CCR4 axis in pediatrics with B-cell acute lymphoblastic leukemia before and after a chemotherapy course (Research Paper)
Acute lymphoblastic leukemia (ALL) is the most common type of pediatrics cancer....Read more
Evaluation of the Therapeutic Potential of a Bifidobacterium longum-Derived Postbiotic in Skin Cancer: Concurrent Assessment of Anticancer and Antioxidant Activities (Research Paper)
Melanoma is one of the most aggressive forms of skin cancer, characterized by ra...Read more
Exploring the biomarker potential of THCAT155 gene with oncogenic function in papillary thyroid carcinoma (Research Paper)
Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, and id...Read more
Extrachromosomal DNA (ecDNA)-Associated Transcription–Replication Conflicts in Cancer: Mechanisms, Synthetic Lethal Vulnerabilities, and Emerging Personalized Therapeutic Strategies (Review)
Unlike chromosomal amplifications, ecDNA molecules cluster within the nucleus, e...Read more
From Clonal Evolution to Relapse: Genomic and Epigenetic Drivers of Treatment Resistance in Pediatric B-Cell Acute Lymphoblastic Leukemia — A Systematic Review (Review)
Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is the most common childho...Read more
From L-Asparaginase Engineering to Precision Medicine: The Role of ASNS in Leukemic Cell Sensitivity (Review)
L-asparaginase is an important therapeutic enzyme used in the treatment of acute...Read more
Fusobacterium nucleatum in Colorectal Cancer: Molecular Crosstalk Between Microbial Virulence and Host Oncogenic Signaling (Review)
According to the World Health Organization (WHO), updated on 13 February 2026, c...Read more
Genetic and Molecular Foundations of Ovarian Cancer: A (Review)
Introduction: Ovarian cancer is one of the deadliest types of cancer affecting w...Read more
Genomic Alterations and Their Role in the Management of Uterine Carcinosarcoma: Focus on TP53 and Biomarker-Guided Therapy (Review)
Uterine carcinosarcoma (UCS) is a rare, highly aggressive malignancy composed of...Read more
Genomic Alterations in Cancer: Implications for Precision Diagnosis and Targeted Therapy (Review)
Cancer is fundamentally a genetic disease driven by the accumulation of genomic ...Read more
Genomic and molecular oncology of colorectal cancer (Review)
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in t...Read more
Genomic Biomarkers in Precision Therapy for Ovarian Cancer: Current Advances, Clinical Challenges, and Future Perspectives (Review)
Ovarian cancer is the most lethal gynecological malignancy, primarily due to lat...Read more
Gut Microbiome and Colorectal Cancer: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities (Review)
Colorectal cancer (CRC) is among the most frequently diagnosed cancers worldwide...Read more
Gut Microbiome–Neural Crosstalk in Cancer: Emerging Implications for Perineural Invasion and Metastatic Progression (Review)
Perineural invasion (PNI), defined as the infiltration of cancer cells into or a...Read more
How Germline DNA-Repair Variants May Influence the Intratumoral Microbiome in Breast Cancer: An Emerging Mechanistic Hypothesis (Review)
Introduction Inherited pathogenic variants in DNA repair genes are important de...Read more
Human Milk miRNAs and Cancer: From Early-Life Molecular Programming to Cancer Risk (Review)
MicroRNAs (miRNAs) are small (21–23 nucleotides), endogenously produced non co...Read more
Identification of Candidate Drugs for Breast Cancer via Transcriptomic Signature Matching Using Connectivity Map (Research Paper)
Breast cancer remains one of the most common malignancies worldwide. Drug repurp...Read more
Identification of HRH1-Associated Candidate Genes Potentially Involved in 5-Fluorouracil Resistance in Colon Cancer: A Bioinformatic Analysis (Research Paper)
Colorectal cancer (CRC) is a major global health burden, with nearly 1.9 million...Read more
Identification of Hub Genes Associated with Tamoxifen Treatment in Recurrent Breast Cancer: An Integrated Bioinformatics Analysis (Research Paper)
Breast cancer is a highly heterogeneous malignancy and a leading cause of cancer...Read more
Identification of key genes involved in the development of human oral squamous cell carcinoma using systems biology (Research Paper)
Oral squamous cell carcinoma is one of the most common malignancies of the head ...Read more
Identification of Survival-Related Genes in Acute Myeloid Leukemia: A Study Based on TCGA Data Analysis (Research Paper)
Acute myeloid leukemia (AML) is the most common leukemia in adults, with a 5-yea...Read more
Immune Checkpoints Dysregulation in Precancerous Colorectal Polyps (Review)
Colorectal cancer (CRC) is one of the most common cancers and a leading cause of...Read more
Immunohistochemical Analysis of Apoptosis (p53/Bax) and Autophagy Markers in Glioblastoma Pathomorphosis Induced by Non-Invasive Phototherapy (Research Paper)
Evaluating the therapeutic pathomorphosis of glioblastoma (GB) through molecular...Read more
Immunotherapy for Cervical Cancer: Mechanistic Insights, Clinical Challenges, and Synergistic Combination Paradigms (Review)
Cervical cancer remains the fourth most common malignancy among women globally, ...Read more
In Silico Transcriptomic Analysis of Radiation-Induced Bystander Effects in Human Fibroblasts: Uncovering Key Regulatory Networks and Ribosome Biogenesis (Research Paper)
Radiation-induced bystander effect (RIBE) represents a non-targeted response in ...Read more
Inhibitory Study of Thyme and Garlic Extracts on Key Receptors in Inflammation and Cancer with a Bioinformatics Approach (Research Paper)
Increasing drug resistance and side effects caused by long-term use of chemical ...Read more
Integrated Multi-Cohort Transcriptomic Analysis Identifies BST2 as a Candidate Immune-Associated Biomarker in Non-Small cell lung cancer (Research Paper)
Lung cancer remains one of the leading causes of cancer-related mortality worldw...Read more
Integrated Multi-Cohort Transcriptomic Analysis Identifies BST2 as a Candidate Immune-Associated Biomarker in Triple-Negative Breast Cancer (Research Paper)
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype char...Read more
Integrating Digital Twin Technology in Precision Oncology: A Nursing Paradigm Shift in Pharmacogenomic Care (Review)
Precision oncology is rapidly evolving, yet the translation of genomic data into...Read more
Integrative Bioinformatic Profiling Reveals microRNA-Driven SOD2 Suppression in Brain Neoplasms (Research Paper)
Brain neoplasms represent a heterogeneous group of tumors with significant molec...Read more
Integrative Network and Variant-Effect Analysis Identifies Candidate Molecular Mediators of Photobiomodulation in Meningeal Lymphatic Endothelium (Research Paper)
Background: Meningeal lymphatic vessels (MLVs) regulate central nervous system f...Read more
Interferon-Related Hub Genes in Resistant Breast Cancer CAFs (Research Paper)
Cancer-associated fibroblasts (CAFs) are important components of the breast canc...Read more
Interpreting Colibactin-Associated Mutational Signatures and pks⁺ Bacterial Detection in Colorectal Cancer: Temporal Discordance and Biomarker Limitations (Review)
Colorectal cancer (CRC) remains a major global health burden. Recent research hi...Read more
Introduction of AOX1 gene as an effective gene in tumorigenesis in thyroid papillary carcinoma (Research Paper)
Papillary thyroid carcinoma (PTC) is the most prevalent form of thyroid cancer a...Read more
Investigating the Effect of Paclitaxel on BAX Gene Expression in MDA-MB-231 Breast Cancer Cell Line (Research Paper)
Triple-Negative Breast Cancer (TNBC) is considered one of the most aggressive su...Read more
Investigating the Effects of miR-204-Enriched Mesenchymal Stem Cell-Derived Exosomes on TGF-β1-Induced EMT in 4T1 Breast Cancer Cells (Research Paper)
Breast cancer is a prevalent disease among females throughout the world. Epithel...Read more
Lack of Correlation Between the CCR5-D32 Mutation and Acute Myeloid Leukemia in Iranian Patients (Research Paper)
Iran is reported as a region with low prevalance for AML [1, 2]. Several studie...Read more
Lactate-Mediated Mechanisms of Cancer Therapy Resistance (Review)
Therapeutic resistance remains a major challenge in cancer treatment and contrib...Read more
LGALS3 as a Potential Therapeutic Target for Endometriosis in an East Asian Population: A Study That Repeats European Drug-Target Mendelian Randomization Findings (Research Paper)
Endometriosis is a disease of the female reproductive system that affects 5-10% ...Read more
Low-Allele-Fraction Pathogenic/Likely Pathogenic Calls in Diagnostic Whole-Exome Sequencing for Hereditary Breast Cancer: A Cautionary Case Series of Sanger Discordance (Research Paper)
Whole-exome sequencing (WES) has become an important tool for germline variant d...Read more
Mechanistic Insights into Long Non-coding RNA-Mediated Gene Regulation Across Human Diseases (Review)
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides that ...Read more
Mesenchymal stem cell derived exosomes as a potential carrier of non-coding RNA in cancer therapy (Review)
Cancer therapies, such as surgical therapy, chemotherapy, and radiotherapy, are ...Read more
Mesenchymal Stem Cell-Derived Exosomal Non-Coding RNAs as Suppressors of Hepatocellular Carcinoma Progression (Review)
Hepatocellular carcinoma (HCC) is a complex disease with diverse etiological cau...Read more
Metabolic–Epigenetic Crosstalk in Human Disease: How Metabolites Control Gene Expression and Cellular Function (Review)
Metabolism and epigenetic regulation are increasingly recognized as interconnect...Read more
miRNA-Mediated Regulation of the NRF2/KEAP1 Pathway in Glioblastoma (Review)
Glioblastoma (GBM) is an aggressive and multifactorial primary brain tumor that ...Read more
Mitomycin and zinc oxide nanoparticle effect on p53 and endothelial growth factor VEGF genes expression in MCF-7 Breast cancer cell line (Research Paper)
Breast cancer is one of the most common invasive cancers affecting women worldwi...Read more
Molecular and Cellular Evaluation of Apoptosis and Tight Junction Proteins (CLDN5/ZO1) in a Glioblastoma-BBB Co-culture Model Following Sensitizer-Free Phototherapy (Research Paper)
Glioblastoma (GB) is an aggressive brain tumor requiring novel therapeutic appro...Read more
Molecular and histopathology study on the effects of Cisplatin and Naringenin in mice with induced breast cancer (Research Paper)
Breast cancer remains one of the most common malignancies and a major cause of m...Read more
Multi-Center Platform for Cancer Detection from Histopathology Images Using Federated Learning (Research Paper)
In connection with the development of deep learning, which became an important s...Read more
Natural Seed Informed and Structure Aware Computational Design of Artificial miRNA Seed Regions Targeting the KRAS 3′UTR (Research Paper)
KRAS is a major cancer-associated oncogene whose dysregulation contributes to th...Read more
Network-Based Identification of Paclitaxel-Associated Targets and Regulatory Mechanisms in HER2-Positive Breast Cancer (Research Paper)
Breast cancer remains one of the most prevalent malignancies globally, with HER2...Read more
Neuro-Cancer Crosstalk in the Tumor Immune Microenvironment: Molecular Mechanisms of Immune Evasion and Tumor-Promoting Inflammation (Review)
The tumor microenvironment (TME) is increasingly recognized as a dynamic ecosyst...Read more
Novel In-Vitro Evaluation of Synergistic Cytotoxicity of Thyme and Garlic Extract on CT26 Colon Cancer Cells (Research Paper)
Colorectal cancer continues to be a leading cause of cancer-related mortality gl...Read more
Nuclear–Mitochondrial Genome Crosstalk in Cancer: Linking Metabolic Reprogramming to Precision Oncology (Review)
Introduction: Mitochondria are major sites of cellular energy metabolism and als...Read more
Nutrition and lifestyle in cancer (Review)
Cancer is defined as a disorder in the normal cell division and growth that lead...Read more
Optimizing Tumor-Stromal Exosome Dose for Enhanced Proliferation in MDA-MB-231 Breast Cancer Cells (Research Paper)
Abstract Background and Aim: Exosomes shed by stromal cells within the tumor mi...Read more
Pancreatic Cancer and DNA Damage Repair Deficiency: Mechanisms, Biomarkers, and Therapeutic Implications (Review)
Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer mo...Read more
Patient-Derived Thyroid Cancer Organoids for Precision Medicine: Preclinical Applications and Emerging Clinical Potential (Review)
Thyroid cancer is the most common endocrine malignancy, and although most patien...Read more
Plant-Derived Berberine and Artesunate as Emerging Therapeutic Candidates Against Human Herpesvirus 8-Driven Kaposi Sarcoma: Molecular Mechanisms and Translational Perspectives (Review)
Human herpesvirus 8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus...Read more
Postbiotics: A New Horizon in Cancer Prevention and Treatment: From Microbiome Modulation to Targeting Tumor Cells (Review)
The complex interaction between the microbiome and the host has increasingly eme...Read more
Precision Genome Editing in Oncology through Base and Prime Editing: Molecular Foundations, Genomic Fidelity, and Therapeutic Prospects (Review)
CRISPR-Cas9 has revolutionized cancer biology by enabling programmable genome ed...Read more
Precision Medicine in Oncology: Molecular Biomarkers and Genomic Strategies for Personalized Cancer Therapy (Review)
Cancer is a complex and heterogeneous disease characterized by diverse molecular...Read more
Processed Pseudogene Dysregulation in Testicular Germ Cell Tumors Reveals High-Contrast Molecular Candidates (Research Paper)
Testicular germ cell tumors (TGCTs) are among the most common malignancies affec...Read more
Proteogenomic Divergence Between mRNA Abundance and Protein Output in Cancer: Implications for Kinase-Centric Pathway Modeling (Review)
Transcriptomic profiling has long anchored pathway analysis in oncology, with mR...Read more
Pseudomonas aeruginosa exotoxin A modulates tumor macrophage-derived exosomal circ_0005519 and the miR-98-5p/IL-10 axis in MCF-7 breast cancer cells (Research Paper)
A breast tumor is more stroma than malignant epithelium, and tumor-associated ma...Read more
Psychological impact of genetic testing for hereditary cancer: A systematic review (Review)
Introduction: Genetic testing for hereditary cancer syndromes such as BRCA1/2 an...Read more
Recombinant oncolytic adenoviruses encoding PD-L1 inhibitors: a novel approach to cancer immunotherapy (Review)
Immune checkpoint inhibitor therapies, especially those targeting the PD-1/PD-L1...Read more
Revisiting the Warburg Effect: Metabolic Plasticity, Lactate Signaling, and Therapeutic Opportunities in Cancer (Review)
The Warburg effect is a hallmark of cancer matabolism characterized by increased...Read more
Role of Antihistamines in Modulating Drug Resistance in Colorectal Cancer (Review)
Colorectal cancer (CRC) is a major global health burden, with nearly 1.9 million...Read more
Role of CRISPR/Cas9 Gene Editing in Targeting CXCR4, CD133 and EpCAM to Inhibit Cell Adhesion and Metastasis in Colorectal Cancer (Review)
Colorectal cancer (CRC) is a major cause of cancer-related mortality, with metas...Read more
Role of Epigenetically Regulated microRNAs in Gemcitabine Resistance in Pancreatic Cancer (Review)
Globally, colorectal cancer (CRC) continues to be the second most deadly kind of...Read more
Role of PDEV in Cancer Immunotherapy (Review)
Plant-derived extracellular vesicles (PDEVs) have attracted considerable attenti...Read more
Roles of Sirtuin-1 in Lung Cancer: From Tumor Progression to Targeted Therapy (Review)
Sirtuins have different roles in several physiological and pathophysiological ac...Read more
scRNA-seq-Derived Transcriptional State Trajectories in EGFR-Mutant Lung Adenocarcinoma: A Critical Review of Therapy-Induced Convergence toward a Slow-Cycling Persister Phenotype (Review)
EGFR tyrosine kinase inhibitors (TKIs) produce initial clinical responses in EGF...Read more
Sequence variation of the Epstein-Barr virus nuclear antigen 1 (EBNA1) gene in chronic lymphocytic leukemia and healthy volunteer subjects (Research Paper)
Epstein-Barr virus (EBV) establishes persistent infection in B cells, and its nu...Read more
Sialic Acid Attenuates Temozolomide-Induced Apoptosis in 1321N1 Glioma Cells via Downregulation of BAX Expression (Research Paper)
Failure of apoptosis is a defining feature of glioma and a major barrier to effe...Read more
Single-Cell and Spatial Multi-Omics in Cancer: Deciphering Tumor Heterogeneity and Advancing Precision Oncology (Review)
Cancer is a highly heterogeneous disease characterized by genetic, epigenetic, t...Read more
Spatial Metabolic Coupling as a Master Regulator of Tumor Metabolic Plasticity and Immune Checkpoint Response: A Multi-Omics Pan-Cancer Analysis (Review)
Cancer metabolism has emerged as a fundamental hallmark of tumor biology, extend...Read more
Spatial Transcriptomic Signatures of ICI Resistance in Solid Tumors: Cellular Niches, Cell–Cell Interactions, and Computational Biomarkers (Review)
The development of immune checkpoint inhibitors (ICIs) that target PD-1, DL1, an...Read more
Splicing impact assessment of canonical splice-site LZTR1 variants of uncertain significance highlights the gap between predicted splice disruption and clinical variant interpretation (Research Paper)
Leucine zipper-like transcription regulator 1 (LZTR1) is a regulator of cellular...Read more
Studying the effects of Cisplatin and Artemisinin on the expression of apoptosis-related genes in mice (Research Paper)
Cisplatin is a chemotherapeutic drug widely used in the treatment of various typ...Read more
Synergistic Effects of Lactobacillus acidophilus-Derived Postbiotics Combined with Chemotherapeutic Agents in Cancer Treatment (Review)
The integration of microbial-derived compounds into cancer therapy has emerged a...Read more
Synergistic Interaction of Resveratrol and Sorafenib in NALM-6 B-Cell Precursor Acute Lymphoblastic Leukemia Cells (Research Paper)
Acute lymphoblastic leukemia (ALL) is a biologically heterogeneous malignancy ch...Read more
Systematic review of the use of Newcastle virus in cancer immunotherapy: molecular mechanisms and clinical perspectives (Review)
Cancer is one of the major public health challenges, and immunotherapy, despite ...Read more
Targeted siRNA delivery in cervical cancer using liposomal nanoparticles (Review)
Cervical cancer is primarily driven by persistent infection with high-risk human...Read more
Targeting Epstein–Barr Virus-Induced Oncogenic Pathways Using Natural Polyphenols: Therapeutic Potential of EGCG and Resveratrol (Review)
Epstein–Barr virus (EBV), a ubiquitous oncogenic gamma-herpesvirus infecting m...Read more
Targeting Metabolic Vulnerabilities in Cancer: From the Warburg Effect to Antiparasitic Drug Repurposing (Review)
Cancer remains a leading cause of death, with conventional treatments limited by...Read more
Targeting the SLC7A11/GSH/GPX4 Axis in Cancer: From Redox Homeostasis to Therapeutic Vulnerability (Review)
Cancer cells continuously adapt their metabolic and redox states to maintain sur...Read more
The Association between Dietary Polyphenols Intake and Risk of Ovarian Cancer: A Systematic Review and Meta-analysis of Observational Studies (Review)
The association between dietary polyphenol subclasses and ovarian cancer risk is...Read more
The Association Between the Gut Microbiome and Cancer Treatment: From Modulation of Therapeutic Response to Microbial Interventions (Review)
Cancer remains one of the major global health challenges. Despite substantial ad...Read more
The cancer–microbiome axis: Mechanisms and emerging therapeutic strategies (Review)
The paradigm of oncology has undergone a fundamental shift, transitioning from a...Read more
The Gut Microbiome as a Modulator of Cancer Immunotherapy: Emerging Roles for Advanced Nursing Nutrition and Care Interventions (Review)
The clinical efficacy of Immune Checkpoint Inhibitors (ICIs) is significantly in...Read more
The Interplay of Intratumoral Microbiome and Lipid Metabolism in the Colorectal Cancer Microenvironment: From Molecular Mechanisms to Therapeutic Perspectives (Review)
The discovery of a rich intratumoral microbiome has revolutionized our understan...Read more
The Intratumoral Microbiome in Cancer: Molecular Mechanisms and Therapeutic Perspectives (Review)
Background: The human microbiome has emerged as a critical modulator of cancer d...Read more
The Mitochondrial Transfer Paradox: A Comparative Transcriptomic and Connectivity Map Profiling of Divergent Fates in Tumor and Immune Cells (Research Paper)
Intercellular mitochondria transfer has emerged as a critical regulator of tissu...Read more
The Nurse's Role in Translating Genomic Findings into Person-Centered Palliative Care Plans for Cancer Patients: A Scoping Review (Review)
Introduction: Rapid advances in genome sequencing technologies have transformed ...Read more
The Role of Artificial Intelligence in Tumor Surgery: A Systematic Review of Clinical Applications, Diagnostic Accuracy, and Postoperative Outcomes (Review)
Tumor surgery, as one of the main pillars of cancer treatment, has always faced ...Read more
The Role of Covert Germline Predisposition and Polygenic Susceptibility in Pediatric Acute Lymphoblastic Leukemia and Their Clinical Implications (Review)
Pediatric acute lymphoblastic leukemia (pALL) is the most common childhood malig...Read more
The Role of Gut Microbiome in Cancer: From Dysbiosis to Non‑Invasive Biomarkers (Review)
The gut microbiome, as a metabolic and immune organ, plays a key role homeostasi...Read more
The role of natural products as adjuvant in immunotherapy of cancer (Review)
The treatment of several cancers has been changed by immunotherapy, which malign...Read more
The Role of Probiotic Yogurt Containing Butyrate Producing Strains in Mitigating Chronic Inflammation and Reducing the Risk of Colon Cancer (Review)
Chronic intestinal inflammation is a well established risk factor for the onset ...Read more
The Role of the Gut Microbiome and Microbial Metabolites in Modulating Responses to Immune Checkpoint Inhibitors (ICIs): A Review of Immunological Mechanisms, Clinical Evidence and Microbiome-Based Therapeutic Strategies (Review)
Immune checkpoint inhibitors (ICIs), particularly antibodies targeting programme...Read more
The Role of the Microbiome in Cancer: From Carcinogenesis to Therapeutic Response (Review)
The human microbiome has emerged as an important component of cancer biology, wi...Read more
The SDF-1 3'A Genetic Variation Is Correlated with Elevated Intra-tumor Tissue and Circulating Concentration of CXCL12 in Glial Tumors (Research Paper)
Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are malignant glia...Read more
The stress-microbiome-cancer triad and the impact of catecholamines on Host-Microbe Interactions and tumor progression (Review)
Two types of psychological stress exist: acute and chronic. The fight or flight ...Read more
Time- and Dose-Dependent Cytotoxic Effects of Cisplatin on MDA-MB-231 Triple-Negative Breast Cancer Cells: An MTT Assay-Based Evaluation of IC₅₀ (Research Paper)
Breast cancer is one of the most common and lethal malignancies worldwide. Among...Read more
TLR3 Genetic Variation in Virus-Related Hepatocellular Carcinoma (Review)
Hepatocellular carcinoma (HCC) is an extremely aggressive cancer with few availa...Read more
TMPRSS15 in Esophageal Carcinoma: A Comprehensive Bioinformatic Analysis of Expression, Diagnostic Value, Prognosis, and Genomic Alterations (Research Paper)
TMPRSS15 (enteropeptidase) is a serine protease primarily involved in intestinal...Read more
TOP2A in Breast and Ovarian Cancer: From a Proliferation Marker to a Potential Mediator of Chemoresistance (Review)
Breast cancer is the most common malignancy among women worldwide, while ovarian...Read more
Torque Teno Virus Coinfection with High-Risk Human Papillomavirus in Cervical Cancer-Related Samples: (Research Paper)
Cervical cancer remains one of the major malignancies associated with persistent...Read more
Transcriptome-Derived Immune Activity in Breast Cancer Reveals Prognostic CCL19–IL10 Expression States with External Evaluation in SCAN-B (Research Paper)
Breast-cancer immune landscapes are heterogeneous, and broad measures of immune ...Read more
Transcriptome-Driven Repurposing of Approved Drugs for Cervical Cancer: A Connectivity Map Approach (Research Paper)
cervical cancer remains one of the most common malignacies in women worldwide,Dr...Read more
Transcriptome-Driven Repurposing of Approved Drugs for Pancreatic Ductal Adenocarcinoma: A Connectivity Map Approach (Research Paper)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Drug ...Read more
Transcriptomic and PPI Network Analysis Reveals Hub Genes in Breast Cancer-Associated Fibroblasts (Research Paper)
Cancer-associated fibroblasts (CAFs) are major components of the breast tumor mi...Read more
Transcriptomic Dissection of Pediatric Brain Tumors: Unraveling the Glial-Stem vs. Neuronal Dichotomy in Ependymoma and Medulloblastoma (Research Paper)
Ependymoma and medulloblastoma are two of the most prevalent pediatric brain mal...Read more
Tumor-Suppressor Checkpoints in Partial Reprogramming: Balancing Epigenetic Rejuvenation, Lineage Fidelity, and Oncogenic Risk (Review)
Partial reprogramming offers a potential route to reverse selected age-associate...Read more
Unraveling the Cellular and Spatial Heterogeneity of Ocular Cancers through Single-Cell and Spatial Omics (Review)
Ocular malignancies, most notably uveal melanoma (UM) and retinoblastoma (RB), a...Read more
When Bacterial Redox Meets Tumor Metabolism: Decoding the Enterococcus faecalis–Cancer Crosstalk (Review)
The metabolic landscape of cancer is increasingly recognized as a dynamic ecosys...Read more
